(Photos) You think it’s the flu, but end up with 90% of your skin affected: Stevens-Johnson syndrome

Por Ignacio Mardones
4 August, 2026

What began with fever, a sore throat, and general malaise ended up becoming a medical emergency that put his life at risk. Within days, his skin began to peel off, and he had to be urgently hospitalized after developing Stevens-Johnson syndrome, one of the most severe reactions that some medications can cause. This is what people who have suffered from the syndrome usually experience.

Stevens-Johnson syndrome is a rare but potentially fatal disease that is usually triggered by an extreme reaction of the body to certain medications—such as antibiotics, anticonvulsants, or painkillers—although it can also be related to some infections. In its early stages, it can be mistaken for the flu, as it causes fever, a sore throat, fatigue, and general discomfort.

However, over the course of hours or days, painful blisters and progressive skin peeling appear, along with lesions on the mucous membranes of the mouth, eyes, nose, and genitals. Because the body loses its main protective barrier, patients are exposed to serious infections, dehydration, and other complications that can put their lives at risk.

Treatment requires immediate hospitalization, often in specialized burn units or intensive care units. Doctors must identify and stop the medication that triggered the reaction as soon as possible, as well as control pain, prevent infections, and keep the patient hydrated.

Although it is a very rare disease, specialists emphasize that recognizing the symptoms in time can make all the difference. If a person develops fever, skin rashes, blisters, or lesions in the mouth and eyes shortly after starting a new medication, it is essential to seek medical attention immediately.

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