Three doses of nanoparticles reduced Alzheimer’s plaques in the brain by between 50% and 60% in less than an hour

Por Josefina Reyes
8 June, 2026

Three doses. One hour. And between 50% and 60% of the proteins that destroy the brain in Alzheimer’s had disappeared.

The result comes from a study published in the journal Signal Transduction and Targeted Therapy, authored by researchers from Spain, China, and the United Kingdom. The technique does not attack neurons directly: it uses nanoparticles that restore the blood-brain barrier, the structure that regulates the brain’s environment. By restoring that barrier, the brain itself reactivates its natural cleaning mechanisms and eliminates beta-amyloid, the central toxic protein in the development of Alzheimer’s.

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What most caught the authors’ attention was the durability: the effects lasted for months. In some cases, behavior after treatment was comparable to that of healthy individuals.

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