캘리는 평범한 개가 아니다. 영국 그레이트 호우드에서 그녀는 사람의 눈으로는 볼 수 없는 무언가를 찾기 위해 소변이 담긴 병의 냄새를 맡으며 하루를 보낸다.
세포가 암세포로 변하면 신진대사가 바뀌고, 몸은 배뇨를 통해 휘발성 유기 화합물을 배출한다. 그것들은 우리에게는 보이지 않는 화학적 흔적이지만, 수억 개의 후각 수용체를 가진 코에는 그렇지 않다. 바로 이때 캘리가 나선다. Medical Detection Dogs와 Open University가 함께 훈련한 캘리는 맹검 검사에서 대장암 환자의 소변과 건강한 사람의 소변을 구별한다.
Bowel cancer detection dog, Callie, identified the odour of the disease in stand 4 and made it very clear to her trainer, Mark, with a stand and stare indication and her signature tippy taps. Callie had actually missed this positive sample in a previous run, as she was working at Spaniel speed and was so excited to be in the room that she didn’t quite sniff the sample at the intensity we know is needed, so Mark put it back in a few runs later and encouraged her to slow down. There was no way she was missing it twice! #medicaldetectiondogs#dogs#fyp#thenoseknows#cancer
양성 샘플을 발견하면, 그녀는 발로 땅을 두드려 신호를 보낸다. 아무도 캘리가 의사를 대체할 것이라고 기대하지 않는다. 그녀의 진정한 가치는 그녀가 밝혀내는 것에 있다. 그녀의 후각이 질병의 분자적 패턴을 분리해 낼 수 있다면, 과학자들은 이를 지도로 활용해 종양이 보이기 전에 조기 비침습적이고 접근 가능한 진단 검사를 설계할 수 있을 것이다.
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